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Current Research

Below is a list of current research studies in HPFT that are open to recruitment. Please get in touch with us if you would like further information, or are interested in taking part.

The adult autism spectrum cohort study – This study seeks to develop a better understanding of the lives of people on the autistic spectrum, as well as their relatives. Participants complete a detailed questionnaire and the information is collated nationally. Sponsor: Northumberland Tyne and Wear NHS Foundation Trust

Identifying the prevalence of antibodies to neuronal membrane targets in first episode psychosis (PPiP) – This study is looking at the proportion of cases of first episode psychosis caused by an immune system problem. The presence of serum neuronal cell antibodies can be associated with psychosis in a small number of cases but the treatment approach and prognosis in such cases would be very different. Sponsor: University of Oxford

E-support for Families of individuals affected by psychosis (COP-e) – To develop and evaluate online resources providing psychological support to carers of people with psychosis and ways to promote carers’ well-being. Sponsor: St George’s, University of London

The Effect of cannabis use on brain function in early psychosis – This study aims to examine whether there are differences in glutamate measures and brain activation in patients with early psychotic illness who use cannabis and those who do not. Sponsor: King’s College London

DeCrypt Study – Delivery of Cognitive Therapy for Young people after Trauma – This study is examining the effectiveness of cognitive therapy in young people with post traumatic stress disorder, compared with treatment as usual. HPFT became involved in 2017 and has been one of the highest recruiters since then. Sponsor: University of East Anglia

Alzheimer’s Disease Genetics Study (AD Genetics) – This study examines genetic factors influencing the presence of early and late onset dementia. Participants and their next of kin are interviewed and have a blood sample taken. Sponsor: Cardiff University

Supporting consolidation of recent memories in Mild Cognitive Impairment – The purpose of the study is to see whether memory aids can be used to support the formation and strengthening of new memories. The total involvement time in the study is 8 weeks. Sponsor: University of Hertfordshire

Spontaneous vs effortful cognition in typical and atypical ageing – This study investigates spontaneous cognition in people with mild cognitive impairment, subjective cognitive decline and healthy older adults, and contrasts them against effortful/strategic processes. Sponsor: University of Hertfordshire

Treatment Resistant Depression (TRD) – This is an observational study of patients who have treatment resistant depression and who have just begun a new treatment (this could be a new medication, therapy or ECT). Sponsor: Janssen.

How people with intellectual disabilities experience transitions under the transforming care programme: a grounded theory story – This study aims to identify what helps people successfully continue living in placements in the community and what might contribute to readmissions. Sponsor: University of Hertfordshire

Methods of diagnosis and services for adults on the autistic spectrum – This is a survey of adults on the autistic spectrum and their relatives and about their experience of current NHS autism diagnostic services. Sponsor: Northumberland Tyne and Wear NHS Foundation Trust

Social information processing in offenders with autistic spectrum disorder – This study examines social problem solving skills among people with Autism Spectrum Disorder and how these areas affect behaviour. Sponsor: University of East Anglia


Research and Your Personal Information

Please follow this link to the Health Research Authority Guidance on how your personal data is used within NHS research


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