8. Substance dependence
8.1 Alcohol dependence
|The drugs listed below are for the acute/initial management of alcohol dependence and withdrawal. For longer term management and relapse prevention service users should be referred to CDAT service run by CRI.|
|Chlordiazepoxide||5mg capsules or tablets||See chlordiazepoxide for alcohol withdrawal regime|
|Thiamine||50mg and 100mg tablets|
|Vitamin B Co strong||Tablets|
|High potency vitamin B complex (Pabrinex)||IM injection||For in-patient use.
Facilities for treating anaphylaxis (including resuscitation facilities should be available when parenteral thiamine is administered.
8.2 Nicotine dependence
|Nicotine||Transdermal patch: Nicorette® Inivsi Patches 25mg, 15mg and 10mg
Lozenges:NiQuitin® Minis Lozenges 1.5mg and 4mg
Inhalation vapour: Nicorette® Inhalator 15mg cartridgesOrodispersible film (strips): NiQuitin® 2.5mg oral filmSublingual tablet: Nicorette® Microtab 2mgNasal spray: Nicorette® 500 microgram per actuationMouth spray: Nicorette® Quickmist 1mg per actuation
|See Nicotine Replacement Therapy Guidelines for Inpatients|
|Varenicline tartrate||500microgram and 1mg tablet.||NICE -TA123 - Varenicline for smoking cessation Named patient request only|
8.3 Opioid dependence
|Treatment of opioid dependence usually requires specialist intervention - generalists who do not have specialist experience should contact CDAT services before attempting to treat opioid dependence.
NICE -TA114 - Methadone and buprenorphine for the management of opioid dependence
|Buprenorphine hydrochloride||400microgram, 2mg and 8mg sublingual tablets||CD. Only in accordance with specialist recommendations.|
|Methadone hydrochloride||1mg/ml SF oral solution||CD. Only in accordance with specialist recommendations.|