8. Substance dependence
8.1 Alcohol dependence
| Alcohol dependence | Preparations | Comments |
| The drugs listed below are for the acute/initial management of alcohol dependence and withdrawal. For longer term management and relapse prevention service users should be referred to CDAT service run by CRI. | ||
| Chlordiazepoxide | 5mg capsules or tablets | See chlordiazepoxide for alcohol withdrawal regime |
| Thiamine | 50mg and 100mg tablets | |
| Vitamin B Co strong | Tablets | |
| High potency vitamin B complex (Pabrinex) | IM injection | For in-patient use. Facilities for treating anaphylaxis (including resuscitation facilities should be available when parenteral thiamine is administered. |
8.2 Nicotine dependence
| Nicotine dependence | Preparations | Comments |
| Nicotine | Transdermal patch: Nicorette® Inivsi Patches 25mg, 15mg and 10mg Lozenges:NiQuitin® Minis Lozenges 1.5mg and 4mg Inhalation vapour: Nicorette® Inhalator 15mg cartridgesOrodispersible film (strips): NiQuitin® 2.5mg oral filmSublingual tablet: Nicorette® Microtab 2mgNasal spray: Nicorette® 500 microgram per actuationMouth spray: Nicorette® Quickmist 1mg per actuation |
See HPFT Nicotine Replacement Therapy Policy for Inpatients |
| Varenicline tartrate | 500microgram and 1mg tablet. | NICE -TA123 - Varenicline for smoking cessation Named patient request only |
8.3 Opioid dependence
| Opioid dependence | Preparations | Comments |
| Treatment of opioid dependence usually requires specialist intervention - generalists who do not have specialist experience should contact Community drugs and alcohol services (CGL) for advice before attempting to treat opioid dependence. NICE -TA114 - Methadone and buprenorphine for the management of opioid dependence |
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| Buprenorphine hydrochloride |
400microgram, 2mg and 8mg sublingual tablets 2mg and 8mg oral lyophilisate tablets (Espranor) |
CD. Only in accordance with specialist recommendations. |
| Methadone hydrochloride | 1mg/ml SF oral solution | CD. Only in accordance with specialist recommendations. |